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| Product Name: |
Milk Thistle Extract
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| Specifications |
Silymarin 80%(UV) Silybin 30%(HPLC) |
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[Appearance] Light yellow powder.
[Specification]Silymarin 80%(UV) Silybin 30%(HPLC)
[Functions]Attempts to isolate the active components of the seed began in 1958. the years later, a research team headed by H.Wagner at the university of Munich was believed to be a single compound. Improved chemical separation methods later revealed that silymarin was not a single component but a complex of chemicals know as flavonolignans. The primary components isolated and structurally characterized from silymarin include silybinin, silydianin and silychristin.
Lots of experiments reported silymarin may be hepatoprotective through a number of mechanisms: antioxidant activity, toxin blockade at the membrane level, enhanced protein synthesis, antifibriotic activity, and possible anti-inflammatory or immunomodulating effects.
Recently, some scientists support silybin is the highest active component in silymarin. But there are diverse opinions.
The research done by Skottova N shows silybin appeared to be responsible for LDL antioxidant effect in vitro in a concentration-dependent manner. Silychristin and silydianin, other flavonolignans of silymarin, acted rather as pro-oxidants.
However, Dr Dvorak Z and his group co***red the cytoprotective effects upon primary human hepatocytes of silymarin extract and its main flavonolignans. The result shows that the best protection was achieved by silydianin and silychristin, and to a lesser degree by silymarin, whilesilybin and isosilybin were less effective.
The work of Zuber R shows all flavonolignans displayed dose-dependent activities in treating liver diseases.
Till now, there has not a clear conclusion. The relation among all flavoniligans is competitive or mixed as revealed by double reciprocal. The studies are continuing.
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| Company: |
Ningbo Gianon Biotech Co.,Ltd.
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| Contact: |
Ms. Chen Lidan |
| Address: |
2103 Building 2# Phenix International Plaza, No.65 Baoshan Road, Beilun Zone, Ningbo, P.R.China |
| Postcode: |
315800 |
| Tel: |
86 574 86818337 |
| Fax: |
86 574 86818226 |
| E-mail: |
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